Allow your patients to sample
Find out more about
how HA works.
are all around us.
1 Results of in vitro study performed to evaluate the release of wetting agents from various silicone hydrogel materials (balafilcon A, senofilcon A and lotrafilcon B) over a 20-hour time period. Lenses were placed in Bausch+Lomb standard lens cases (or hydrogen peroxide neutralizing cases) and soaked for 8 hours in respective lens care solutions. Hanks’ balanced salt solution (HBSS) was dripped over the lenses at a rate that approximates tear secretion in the human eye as determined by Reddy I, et al. Ocular Therapeutics and Drug Delivery. The solution that rinsed off the lenses was collected at set time periods over 20 hours and the surface tension was measured using teniometry. The surface tensions of the rinse solution collected were then analyzed versus the surface tension of the control (rinse solutions collected from lenses pre-soaked in HBSS) using a t-test and a p-value ≤ 0.05. This data represents the number of hours across which a consistent statistical difference in average surface tension could be detected between surface tension of HBSS and the surface tension of the rinse solution from lenses that had been soaked in various lens care solutions for all three silicone hydrogel lens types tested.
3 Results from a clinical trial in which a total of 291 subjects were enrolled wearing a range of marketed soft contact lenses and using various soft contact lens care products. Subjects were dispensed Biotrue and participated in a CAWI (Computer Aided Web Interviewing) between day 7 and day 11 of the clinical trial. Subject responses were measured using a six-point Likert Scale in which 1 = strongly disagree and 6 = strongly agree. Results represent reported percentage agreement ratings.
4 Results of in vitro study performed to evaluate the rate of release of sodium hyaluronan (HA) from both traditional hydrogel (Bausch + Lomb SofLens®38 contact lenses, SofLens for Astigmatism lenses, and Vistakon ACUVUE 2) and silicone hydrogel contact lenses (Bausch + Lomb PureVision® contact lenses, Vistakon ACUVUE Oasys, Vistakon ACUVUE Advance, CIBA O 2OPTIX, CIBA Night & Day, and CooperVision Biofinity) over a 20-hour time period. Lenses were placed in Bausch + Lomb standard lenses cases and soaked overnight in Biotrue prepared with HA tagged with fluorescein. Hank’s balanced salt solution (HBSS) was dripped over the lenses at a rate that approximates tear film secretion in the human eye as determined by Reddy I, et al. Ocular Therapeutics and Drug Delivery. Technomic Publishing Co. 1996; 174. The solution that rinsed off the lenses was collected hourly over a 20-hour period and the fluorescence intensity was detected. A standard curve was used to determine the concentration of fluorescein-tagged HA present in each rinse solution. The extended presence of fluorescein-tagged HA in the rinse solutions indicates the percent of HA retained on the lens surface.